Semanage port -a -t mail_port_t -p tcp 24242 I haven't tested everything but I was able to create new users and send mail between them without any errors. Hello, I just want to report that I was able to run iRedMail with SELinux in enforcing mode. Related original log or error message is required if you're experiencing an issue. Manage mail accounts with iRedAdmin-Pro? No Store mail accounts in which backend (LDAP/MySQL/PGSQL): MySQL Linux/BSD distribution name and version: RockyLinux 8.5 Deployed with iRedMail Easy or the downloadable installer? downloadable installer iRedMail version (check /etc/iredmail-release): 1.5.1 = REQUIRED BASIC INFO OF YOUR IREDMAIL SERVER =